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The culprit is the rapid weight loss itself, which triggers a temporary type of shedding called telogen effluvium

Retreatment with peginterferon plus ribavirin with the aim of eradicating HCV is not indicated in patients who have failed to respond to a prior course of peginterferon plus ribavirin, even if a different type of peginterferon is administered (III) Special Patient Groups The majority of HCV treatment trials were conducted among highly selected patient populations making it difficult to predict the safety and efficacy of existing therapy in many settings